En juin 2013, IDW publie une saison 10 de la série avec Joe Harris à la tête du projet.
Chaque mois, un numéro est publié reprenant la série après le second film I Want To Believe. Chris Carter supervise les scripts quoiqu’on doute un peu de sa vraie implication. Joe Harris propose une saison 10 qui tente de retrouver l’esprit old school de la série en balayant et corrigeant les événements passés comme le sort réservé à Krycek, à l’Homme à la Cigarette, la situation professionnelle de Mulder et Scully. Harris garde pourtant une mythologie cohérente en faisant évoluer les super soldats vers une mythologie plus proche des saisons précédentes, seul bon point évident de cette saison 10.
| Believers, Part 1 | 1 | 19 juin 2013 | Scénario: Joe Harris with Chris Carter | Dessins: Michael Walsh |
 | Fox Mulder and Dana Scully—now living together in Spotsylvania County, Virginia under the aliases Anthony and Dana Blake—are visited by Deputy Director Walter Skinner, who informs them that an unknown person hacked into the FBI’s files and discovered information regarding the X-Files. Skinner is later nearly killed in his hotel room, whereas Scully is met outside of the hospital by one of her patients, the young Emily Van de Kamp who is acting as if she were possessed; Scully is soon surrounded and brutally attacked. | |||
| Believers, Part 2 | 2 | 24 juillet 2013 | Scénario: Joe Harris with Chris Carter | Dessins: Michael Walsh |
 | FBI Agent John Doggett investigates a pipeline that mysteriously explodes. Meanwhile, Mulder tracks down the Lone Gunmen—revealed to have faked their deaths several years earlier—who attempt to help him find Scully. Scully, meanwhile, wakes up in a cabin surrounded by the mysterious Acolytes. She is subsequently saved by the ominous Deacon. | |||
| Believers, Part 3 | 3 | 21 août 2013 | Scénario: Joe Harris with Chris Carter | Dessins: Michael Walsh |
 | FBI Agent Monica Reyes investigates William’s adoptive parents, only to discover their dead bodies in William’s room, revealing that it was some unknown entities portraying the adoptive parents. Scully learns that she is being protected by the Deacon, and that the pipeline that Dogget was investigating is carrying magnetite. Mulder is visited by the believed-to-be dead Smoking Man, who behaves extremely oddly. Skinner tracks down Emily, only to discover tell-tale signs of acidic green alien blood. | |||
| Believers, Part 4 | 4 | 18 septembre 2013 | Scénario: Joe Harris with Chris Carter | Dessins: Michael Walsh |
 | Mulder visits the pipeline believed to be carrying magnetite and deduces that Scully has been taken into the surrounding woods. Meanwhile, Scully is taken by the Deacon to a general store, where she is picked up by an officer, who turns out to be a shape-shifting Acolyte; he transforms into Mulder, and Scully crashes the car. In the woods, Scully shoots the real Mulder, believing him to be Deacon. | |||
| Believers, Part 5 | 5 | 16 octobre 2013 | Scénario: Joe Harris with Chris Carter | Dessins: Michael Walsh |
 | Mulder is healed by the Acolytes only to be tricked into thinking one of them is Scully. The real Scully, however manages to kill the impostor; suddenly she witnesses a massive alien space ship rise from the center of Yellowstone National Park, but begins to forget the encounter. She reports to an FBI review board, headed by Skinner, and argues that people with connections to the X-Files division are systematically being targeted. To counter this, the FBI decides to reinstate Mulder and Scully as federal agents. | |||
| Hosts, Part 1 | 6 | 27 novembre 2013 | Scénario: Joe Harris | Dessins: Elena Casagrande with Silvia Califano |
 | Before they can remove the furniture coverings from their basement office at the FBI, Agents Mulder and Scully are summoned to a meeting and introduced to their new supervisor, Assistant Director Anna Morales, intent on streamlining the newly reopened X-Files unit. She sends Scully to Quantico, VA and Mulder to Martha’s Vineyard to solve a case that has haunting similarities to their decades-old investigation into the Flukeman. Together they make dangerous revelations about the humanoid flatworm’s ability to regenerate and procreate. | |||
| Hosts, Part 2 | 7 | 11 décembre 2013 | Scénario: Joe Harris | Dessins: Elena Casagrande with Silvia Califano |
 | Mulder survives a massive Flukeman attack in the sewers beneath Martha’s Vineyard thanks to Scully’s surgical skills, but he has developed an unnerving psychic connection to the creatures, providing him with a greater understanding of the nature of the organisms and their connection to the 1986 Chernobyl disaster. | |||
| Being for the Benefit of Mr. X | 8 | 8 janvier 2014 | Scénario: Joe Harris | Dessins: Michael Walsh |
 | Mulder and Scully ditch their reinstatement training after receiving a voicemail originating from Mulder’s old apartment. The clues lead them to revelations about their enemies and the project code named Purity Control. Meanwhile, flashbacks shed new light on the motives behind Mulder’s past informants and the source trying to contact him now. | |||
| Chitter | 9 | 12 février 2014 | Scénario: Joe Harris | Dessins: Greg Scott |
 | The agents pursue a missing person’s case in Millersburg, Pennsylvania in which the prime suspect might be under the control of the Chittering God, a being that feeds on its victims’ despair. But what Scully discovers about this entity might be less frightening than what she discovers about herself. | |||
| More Musings of a Cigarette Smoking Man | 10 | 12 mars 2014 | Scénario: Joe Harris | Dessins: menton3 avec Tony Moy |
 | The man who spent his life hiding the truth from the public will now have to uncover it if he is to make sense of how he mysteriously returned from the dead. | |||
| Pilgrims, Part 1 | 11 | 30 avril 2014 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
| | The shifting sands of Saudi Arabia have attracted pilgrims, consumed armies, and made men rich beyond their wildest dreams. But when an ancient weapon is discovered beneath a newly tapped oil field, Agents Mulder and Scully find themselves pulled back into a black game as slippery as the X-Files have ever revealed… and you won’t believe who’s turning up to join them. | |||
| Pilgrims, Part 2 | 12 | 28 mai 2014 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | The dreaded black oil has been tapped in the remote deserts of the Middle East, and divergent forces are massing to contain, control, and even assist the deadly, sentient essence of Earth’s once (and future?) alien colonists. But what does it want with Agents Mulder and Scully, what does a rising neo-Syndicate want with it? And why, where, and—most importantly—how is Alex Krycek involved?! | |||
| Pilgrims, Part 3 | 13 | 25-juin-14 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | “Black oil” has returned and along with it, the long-dead double agent Alex Krycek. In order to solve the mystery of Krycek’s return, Mulder and Scully seek help from the Lone Gunmen, who seem to have trouble of their own. | |||
| Pilgrims, Part 4 | 14 | 23 juillet 2014 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | Agent Mulder has been infected with black oil, playing host to an alien being seeking to use his knowledge, history, and expertise to unlock something mysteriously and terribly powerful. But Mulder and the would-be alien colonist possessing him aren’t the only ones looking for it… | |||
| Pilgrims, Part 5 | 15 | 13 août 2014 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | Flying saucers, the Cigarette Smoking Man, the New Syndicate… this mind-blowing conclusion sets the agenda for the rest of Season 10. Don’t miss the series that Geeked Out Nation says holds ‘nearly as much quality and charm as its small screen predecessor ever did.’ | |||
| Immaculate, Part 1 | 16 | 17 septembre 2014 | Scénario: Joe Harris | Dessins: Colin Lorimer |
 | An abortion clinic bombing leads Scully and Mulder to investigate a right-wing extremist group helmed by a teenage girl who claims to hear the voice of God in her head. But her actions are far from heavenly… | |||
| Immaculate, Part 2 | 17 | 22 octobre 2014 | Scénario: Joe Harris | Dessins: Colin Lorimer |
 | An abortion clinic bombing has led Scully and Mulder to investigate a right-wing extremist group helmed by a teenage girl who claims to hear the voice of God in her head. But her actions are far from heavenly… Plus, a special guest star you’ll never see coming! | |||
| Monica & John | 18 | 12 novembre 2014 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | When we last saw them, Special Agents John Doggett and Monica Reyes seemingly met their final fates at the hands of the alien faction known as the Acolytes. Now in this one-off story, we’ll reveal what actually became of them and what is in store for them next. | |||
| G-23, Part 1 | 19 | 3 décembre 2014 | Scénario: Joe Harris | Dessins: Tom Mandrake |
 | A government plot leads Mulder to ponder his early days as a cadet at Quantico, including his relationship with Diana Fowley and the fateful day that he found the iconic I Want to Believe poster. But the intrigue goes even further back in time, to when Bill Mulder was partnered with the Cigarette Smoking Man. | |||
| G-23, Part 2 | 20 | 28 janvier 2015 | Scénario: Joe Harris | Dessins: Tom Mandrake |
 | A government plot leads Mulder to ponder his early days as a cadet at Quantico, including his relationship with Diana Fowley and the fateful day that he found the iconic I Want to Believe poster. But the intrigue goes even further back in time, to when Bill Mulder was partnered with the Cigarette Smoking Man. | |||
| Elders, Part 1 | 21 | 18 mars 2015 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | For as long as humanity has known of the alien plot to re-colonize the Earth, there have been men who would conspire to consolidate that knowledge, and the power that came with it, for themselves. But the Syndicate that long bedeviled Agents Mulder and Scully are no more, consumed and destroyed by those very secrets they kept… or are they? What new secrets will they fight and kill for? And what will become of the X-Files once those secrets are laid bare? The end begins here! | |||
| Elders, Part 2 | 22 | 1 avril 2015 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | The ‘Syndicate’ that long bedeviled Agents Mulder and Scully has returned with old faces and a new leader. | |||
| Elders, Part 3 | 23 | 15 avril 2015 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | The Syndicate has returned with familiar faces and a new leader. Their first order of business: shutting down the X-Files for good | |||
| Elders, Part 4 | 24 | 13 mai 2015 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | The penultimate chapter of Season 10! Mulder has come face to face with the mysterious leader of the resurrected Syndicate and learned many of its secrets. But will he survive the experience? | |||
| Elders, Part 5 | 25 | 24 juin 2015 | Scénario: Joe Harris | Dessins: Matthew Dow Smith |
 | Double-sized finale of ‘Season 10!’ Clandestine plans come to a roaring boil as things heat up for Mulder and Scully, who will never be the same after this issue! | |||